[Application of autologous fibrin glue for skull base defect closure in transsphenoidal surgery. Case report and literature review]. / Primenenie autologichnogo fibrinovogo kleya dlya plastiki defekta osnovaniya cherepa v transsfenoidal'noi khirurgii. Opisanie klinicheskogo sluchaya i obzor literatury.

Nasal CSF leakage is the most common complication after transsphenoidal surgery, especially in case of extended transsphenoidal access. It is one of the main and obvious risk factors of meningitis. Introduction of effective reconstructive techniques made it possible to reduce the incidence of postoperative CSF leakage. Fibrin glue is one of the main components in transsphenoidal surgery for skull base defect closure. The use of autologous fibrin glue excludes immune response due to its biocompatibility. Modern technologies of preparation of autologous fibrin glue make it possible to obtain a large volume of glue that ensures complete sealing of skull base defect. At the same time, autologous glue contains factors promoting rapid tissue regeneration. It is of great importance for engraftment of autologous transplants in the area of skull base defect.

[Endoscopic fenestration of arachnoid cyst of posterior cranial fossa through third ventriculostomy]. / Endoskopicheskaya fenestratsiya arakhnoidal'noi kisty zadnei cherepnoi yamki cherez triventrikulostomu.

Arachnoid cysts (AC) are spaces with cerebrospinal fluid covered with arachnoid membrane. Most cysts are supratentorial and only 10-12% of ACs are found in posterior cranial fossa. This disease is usually diagnosed in childhood. In adults, ACs make up 1.4% of all focal lesions. ACs of posterior cranial fossa are often localized behind the cerebellum or in cerebellopontine angle. Most patients with cysts do not have permanent symptoms and should be followed-up. Surgery is indicated for cysts complicated by focal and hydrocephalic-hypertension symptoms. Microsurgical or endoscopic procedures are used. Surgical approach is determined by the closest location of cyst to brain surface. The authors report non-standard surgical approach for giant AC of posterior cranial fossa complicated by obstructive hydrocephalus, intracranial hypertension and visual function impairment. Endoscopic third ventriculostomy was followed by AC fenestration through ventriculostomy. Symptoms disappeared within 6 months after surgery.